Independent. No paid placement. Reviewed weekly Editorial policy Newsletter

Most of what you read about peptides is written by someone selling them.

We explain what these ingredients do, what they don't, and how strong the evidence actually is — in plain English, with the sources attached. We don't take money from anyone we write about.

What that means in practice

  • No sponsored placements, ever
  • Every claim carries a citation you can check
  • We publish what the evidence doesn't support
  • Corrections logged in public

New to peptides

Peptide skincare for beginners

Start with one peptide, at a stated percentage, for twelve weeks. Almost every mistake is starting with too many products at once.

Read the guide →

Most asked

Do copper peptides actually work?

Short answer: yes for firmness and fine lines. No for hair, acne, or anything injected.

Read the verdict →

Buying guide

What percentage of peptide should a serum contain?

3% for Matrixyl, 10% for Argireline in the trial that produced its headline result. Most brands won't tell you either.

Read the guide →

Recently updated

Legal status tracker →

11 September 2026

Copper peptides vs retinol

You don't have to choose. We also say plainly where the published advice contradicts itself.

11 September 2026

How to use copper peptides

One real incompatibility, and it isn't the one most articles warn you about.

8 September 2026

FDA status: what changed in 2026

Twelve peptides left Category 2 in April. That is not the same as becoming legal, and the difference matters.

New to the whole topic

All ingredients →

Start here

What is a peptide?

A short chain of amino acids — the same building blocks as proteins, just fewer of them. The plain answer, without the jargon.

The closest thing to a verdict

Are peptides worth it?

Yes, for two or three specific things. No, for most of what's loudly marketed under the same word. Which is which, by name.

Ingestible

Do collagen peptides actually work?

Genuinely better evidence than most supplements — with the honest caveat about who funded the trials.

Matrixyl and Argireline

All ingredients →

Grade A evidence

Matrixyl 3000

Around 20% reduction in wrinkle depth at 3% — but most of the testing behind that figure is the manufacturer's own.

Grade B evidence

Argireline

Marketed as "Botox in a bottle." At the tested 10% it has a real effect. Most products use far less.

Comparison

Matrixyl vs Argireline

Different jobs, not competing products — one for collagen loss, one for expression lines.